Religen Inc.

FRAT®(Folate Receptor Autoantibody Test) is a diagnostic blood test that screens for autoantibodies to the Folate Receptor Alpha (FRa), known as Folate Receptor Autoantibodies.

The presence of Folate Receptor Autoantibodies suggests that folate (vitamin B9), which is an essential vitamin for proper growth and neurological function, is not being properly transported to the brain and into cerebrospinal fluid (CSF), among other tissues where Folate Receptor Alpha may be found.

The early detection of folate receptor autoantibodies is necessary because it can lead to timely diagnosis and appropriate management of conditions associated with these autoantibodies. Folate receptor autoantibodies have been found in Cerebral Folate Deficiency Syndrome, Autism Spectrum Disorders, Schizophrenia, Depression and Neural Tube Defects, among other neurodevelopmental disorders.

The timely initiation of appropriate treatment, such as alternate reduced folates and/or dietary adjustments, may lead to optimal outcomes and improved overall prognosis for the individual.

As with any medical test, the interpretation of the results and the subsequent treatment plan should be discussed with a qualified healthcare professional.